Based on the best-selling novel by Jodi Picoult, the film adaptation of "My Sister's Keeper" stars Cameron Diaz, Abigail Breslin and Sofia Vassilieva. Sara Fitzgerald (Diaz) has two daughters, 11-year-old Anna (Breslin) and a teenager, Kate (Vassilieva). Kate has leukemia, and Sara had Anna with the intention that she would be a donor of blood, marrow, etc. to her older sister. However when Kate's kidneys begin to fail, Anna shocks the family by seeing a lawyer (Alec Baldwin) about not having to donate one of her kidneys to her sister.