Seth Rogen and James Franco star as buddies in this stoner comedy from Judd Apatow. Dale (Rogen) is a process server whose drug dealer Saul (Franco) sells him a special kind of marijuana called Pineapple Express. When Dale goes to serve a summons, he witnesses a murder carried out by a drug lord (Gary Cole) and a corrupt cop (Rosie Perez). In shock and scared for his life, Dale flees, but he leaves behind a roach that the killers link back to Saul. Consequently the two men go on the run together, some incompetent hitmen in their pursuit.