An ordinary man with an extraordinary gift must save the planet from evil in this action-packed fantasy. Unknown to most people, the world is crowded with spirits both good and evil who walk among us in human guise. One of the few who can see these spirits is John Constantine (Keanu Reeves), but the responsibility of his vision is more than he can stand, and he tries to kill himself. Saved from death, Constantine must now atone for his actions by acting as a guardian in the middle ground between Paradise and Hell. Constantine also makes the acquaintance of Angela Dodson (Rachel Weisz), a police detective who becomes aware of his unusual gift while looking into the death of her sister; he leads her into the unknown world of the spirits and soon circumstances demand that they join forces in a desperate bid to save humanity from evil.